Effect of Rose oil on Gastro-esophageal Reflux Disease in comparison with omeprazole capsule
- Conditions
- Gastro-esophageal reflux disease.Gastro-oesophageal reflux disease
- Registration Number
- IRCT2014101119489N1
- Lead Sponsor
- Tehran University of Medical Sciences, Vice chancellor for research and technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Patients between 16 to 80 years old; Patients have at least 12 weeks history of GERD; No history of barrett's esophagus; No history of surgery on esophagus or stomach; No history of any cancer in esophagus, stomach or abdomen; No coagulation problem unable to withdrawal of drugs; No use of glucocorticoids and NSAIDs more than 3 days a week during last 28 days; No sucralfate use during 3 days before study; No aspirin use more than 150 mg daily; No active peptic ulcer or its complications; No antibiotic use for H. pylori eradication during last 28 days; No Cigarette smoking or alcohol drinking; Absence of any GERD complication.
Exclusion criteria:
Appearance of drug adverse effects; Loss of patient compliance
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umbers of regurgitation episodes. Timepoint: Onset of intervention and 10 and 20 days later. Method of measurement: History taking.;Numbers of heartburn episodes. Timepoint: Onset of intervention and 10 and 20 days later. Method of measurement: History taking.;Severity of regurgitations. Timepoint: Onset of intervention and twice 10 and 20 days later. Method of measurement: History taking.;Severity of heartburns. Timepoint: Onset of intervention and 10 and 20 days later. Method of measurement: History taking.
- Secondary Outcome Measures
Name Time Method Age. Timepoint: at the beginning of the survey. Method of measurement: ID information.;Sex. Timepoint: at the beginning of the survey. Method of measurement: inspection.;Duration of drug use. Timepoint: In 10 days intervals. Method of measurement: Patient statements.;Side effects. Timepoint: Twice in 10-day intervals. Method of measurement: History and physical exams.