Precision Vaccine Promotion in Underserved Populations

Not Applicable

Completed

• Conditions: Influenza; Vaccine Hesitancy

• Registration Number: NCT05537441
• Lead Sponsor: University of Southern California

Brief Summary

Previous studies have shown that low-cost, behavioral nudges through texting can increase influenza vaccination uptake compared to usual care. However, there are limited studies that evaluate the effect of decreasing barriers to scheduling, especially within safety net populations. The setting for this study, DHS, is the second largest public delivery system in the country and serves approximately half a million diverse patients that are eligible for vaccinations annually. This pilot study (one arm in a larger randomized controlled trial) will examine the effect of text messages highlighting MediCal health plan transportation resources (vs standard text messaging) on influenza vaccination rates in adults during the 2022-2023 flu season.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2022-09-09
• Study First Submitted QC: 2022-09-09
• Study First Posted: 2022-09-13
• Study Start: 2022-09-22
• Primary Completion: 2023-03-31
• Study Completion: 2023-06-01
• Results First Submitted: 2024-06-01
• Status Verified: 2024-09
• Results First Submitted QC: 2024-09-25
• Last Update Submitted: 2024-09-25
• Results First Posted: 2024-09-30
• Last Update Posted: 2024-09-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 228831

Inclusion Criteria

• Los Angeles County Department of Health Services (LACDHS) primary care patients over 6 months of age

Exclusion Criteria

• LACDHS patients less than 6 months of age

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Number of Participants Vaccinated at the End of the Campaign Period	6 months	Number of Participants who received their influenza vaccination during the campaign period, as measured in the California Immunization Registry (CAIR2) to include vaccinations occurring both inside and outside the LADHS system. We assessed baseline vaccination status at the beginning of the flu season and excluded individuals who already received their vaccination.

Secondary Outcome Measures

Name	Time	Method
Heterogeneity of Treatment Effects for Demographics	6 months	Heterogeneity of treatment effects for demographic groups (previous vaccination status: vaccinated or unvaccinated)

Trial Locations

Locations (1)

Los Angeles County Department of Health Services; 🇺🇸 Los Angeles, California, United States