High-fat Yogurt and Plasma Lipids Profile

Not Applicable

Completed

• Conditions: Plasma Lipid Profile
• Interventions: Other: saturated fat intake

• Registration Number: NCT05589350
• Lead Sponsor: Shahid Beheshti University

Brief Summary

The goal of this clinical trial is to compare the effect of saturated fat intake from different source on cardiometabolic risk markers in healthy subjects. The main question it aims to answer are:

-Does intake of saturated fat in the form of high-fat yogurt have a different effect on cardiometabolic risk factors than intake of the same amount from butter? In this study, in two periods of 4 weeks, the effect of receiving saturated fat from high-fat yogurt compared to receiving the same amount of saturated fat from butter and low-fat yogurt on the plasma concentration of lipids, cholesterol, insulin, and some inflammatory factors will be studied in healthy subjects.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-15
• Study First Submitted: 2022-10-15
• Study First Submitted QC: 2022-10-18
• Study First Posted: 2022-10-21
• Status Verified: 2023-04
• Primary Completion: 2023-04-13
• Study Completion: 2023-04-13
• Last Update Submitted: 2023-04-14
• Last Update Posted: 2023-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Healthy people who do not use lipid-lowering, blood pressure control or diabetes medications

Exclusion Criteria

• Taking supplements of omega-3 fatty acids, or antioxidants

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
High-fat yogurt	saturated fat intake	Daily consumption of 1-2 servings (based on daily calorie requirement) of high-fat yogurt
Low-fat yogurt and butter	saturated fat intake	Daily consumption of 1-2 servings of low-fat yogurt along with daily consumption of about 10 grams of animal butter

Primary Outcome Measures

Name	Time	Method
Plasma lipid profile	4 weeks	Plasma concentrations of cholesterol, high-density lipoprotein cholesterol, Low-density lipoprotein cholesterol, and triglyceride

Secondary Outcome Measures

Name	Time	Method
Glycemic measures	4 weeks	Fasting plasma concentrations of glucose and insulin

Trial Locations

Locations (1)

Clinical Nutrition Research Unit, National Nutrition and Food Technology Research Institute; 🇮🇷 Tehran, Iran, Islamic Republic of