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Can a rapid screening strategy improve infection control in critically ill patients?

Not Applicable
Completed
Conditions
Infection by ESBL or CPE bacteria
Infections and Infestations
Registration Number
ISRCTN23588440
Lead Sponsor
Hôpitaux Universitaires de Genève
Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35672757/ (added 08/06/2022)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
101
Inclusion Criteria

All patients admitted to the Intensive Care Units during the study period

Exclusion Criteria

N/A

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
nnecessary pre-emptive isolation-days will be determined using Turn-Around-Times for ESBL/CPE screening and work up, with the help of computerized laboratory databases and a specific tool integrated into the electronic patient file, informed in real time by patient dedicated nurses. This outcome will be measured for all high-risk patient with a negative result for ESBL and CPE on a targeted screening at admission, at the time of discontinuation of pre-emptive isolation.
Secondary Outcome Measures
NameTimeMethod
<br> 1. Time between patient screening and implementation of contact precaution of previously unknown ESBL-PE and CPE carriers will be determined using Turn-Around-Times for ESBL/CPE screening and work up, with the help of computerized laboratory databases and a specific tool integrated into the electronic patient file, informed in real time by patient dedicated nurses. This outcome will be measured for all patients newly positive for ESBL and CPE on a weekly screening, at the time of implementation of contact precaution.<br> 2. Adjusted incidence-density ratio of nosocomial ESBL/CPE acquisition will be determined using surveillance data prospectively collected by infection control nurses. This outcome will be measured monthly.<br>
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