Attention Bias Modification Treatment for Major Depressive Disorder in Adolescents: A Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Major Depressive Disorder, Single Episode, Unspecified
- Sponsor
- Hunan Normal University
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Changes in depressive symptom number
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
In this study, we test whether a two-week 8-session neutral attention bias modification (ABM) training and a two-week 4-session positive ABM could reduce depressive symptoms relative to placebo controls in adolescents with major depressive disorder at posttraining and follow-ups during one year.
Detailed Description
Depression is a common health problem in adolescents. Negative attentional bias has been theorized to play a critical role in the onset and maintenance of depression, suggesting that reduction of such biases may treat symptoms of depression. Recent studies have shown that attention bias modification(ABM) training could reduce depressive symptoms in both dysphoria and previously depressed adult patients.To test the effectiveness of ABM training on the treatment of depressive symptoms in depressed adolescents, we designed a randomized, double-blind, placebo controlled trial in adolescents with major depressive disorder(MDD).
Investigators
Wenhui Yang
Department of Psychology
Hunan Normal University
Eligibility Criteria
Inclusion Criteria
- •Meet the major depression disorder's criteria
Exclusion Criteria
- •bipolar disorder, schizophrenia or organic mental disorder;
- •any concurrent psychotherapy;
- •any concurrent psychotropic medication.
Outcomes
Primary Outcomes
Changes in depressive symptom number
Time Frame: baseline, 7-week, 6-month follow-up
Depressive symptom accounts measured by Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children.
Changes in depressive severity
Time Frame: baseline, 7-week, 6-month follow-up
depressive severity measured by the construct interview of the Schedule for Affective Disorders and Schizophrenia for School-Age Children(K-SADS)
Secondary Outcomes
- Diagnostic status of major depressive disorder(baseline, 7-week, 6-month follow-up)
- Change of Self-report symptoms(baseline, 7-week, 6-, 12-month follow-up)