Comparative evaluation of Diode laser and Photoactivated disinfection on endodontic treatment outcome – A Randomized Controlled Clinical Trial.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Post operative pain
研究概览
简要总结
The effectiveness of endodontic treatment largely depends on the removal of bacteria and irritants from the root canal prior to obturation. Chemical debridement aids in the elimination of residual tissue and bacterial biofilm, particularly from the non-instrumented region of the root canal system. In recent year, intracanal laser has emerged as an adjunctive treatment for endodontic procedure. The aim of this randomized controlled trial is to evaluate the difference in postoperative pain and periapical healing following root canal treatment with diode laser and photoactivated disinfection used for root canal irrigation. The null hypothesis is that there is no significant difference in postoperative pain and periapical healing between the two treatment methods.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients must agree to participate, single rooted teeth with pulp necrosis and symptomatic apical periodontitis, Radiographic evidence of periapical radiolucency with PAI score more than or equal to three.
排除标准
- •Teeth with immature roots.
- •Calcified canals.
- •Poor restorative, or periodontal prognosis.
- •Antibiotic use within the last month.
- •Anti-inflammatory analgesic use within the last 5 days.
- •Patients with any uncontrolled systemic disease.
- •Pregnant or Lactating females.
结局指标
主要结局
Post operative pain
时间窗: 4, 24, 48, and 72-hour postoperative intervals.
次要结局
- Periapical healing(3, 6 and 12 months after root canal treatment.)