The Effect of an Increased Intake of Antioxidant-rich Foods on Training Adaptation, Redox-balance and Inflammation Among Elite Athletes During a Moderate Altitude Training Camp
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 35
- 试验地点
- 3
- 主要终点
- Training adaptation
研究概览
简要总结
Athletes, especially in endurance sports, are at increased risk of oxidative stress and inflammation-related diseases and injuries. The production of reactive oxygen and nitrogen species (RONS) and inflammatory markers increase during exercise and especially during altitude training. Antioxidant supplementation is commonly used among athletes in the belief that it prevents oxidative stress and oxidative damage. A transient increase of RONS is however necessary to activate signaling cascades initiating training adaptation. Antioxidant supplementation has been shown to inhibit the exercise effects in several independent studies, possibly by interfering/reducing the signal cascades initiated by RONS. However, it is unknown whether a high intake of antioxidant rich foods can affect the amount of RONS, inflammation markers and/or training adaptation. The investigators want to examine whether an increased intake of natural antioxidants in the form of antioxidant-rich foods fruits, vegetables and berries, in line with the official Norwegian dietary advice can affect antioxidant status, immune function and training adaptation associated with altitude training in Norwegian elite athletes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 16 Years 至 42 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •National team athletes, summer endurance sports
排除标准
- •Allergies in conflict with the intervention foods
- •Use of medication that could affect training and performance
- •Injuries that could affect training and performance
结局指标
主要结局
Training adaptation
时间窗: Measured one week before, and one week after the moderate altitude training camp
change in Vo2-max
Percent change in performance (sport specific tests will be aggregated to one outcome by the use of percent change)
时间窗: Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp
Cycling: 10 000 m on a bike roller; Rowing: 2000 meter on Concept2-apparatus; Paddling: 1000 meter Concept2-apparatus; Swimming: 200 meter
Training adaptation for swimmers
时间窗: Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp
For swimming only: 100 meter max speed
次要结局
- Bone mineral density(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- change in body composition(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Dietary intake (change in food and nutrient intake)(Measured one and three week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Change in biomarkers of inflammation(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- change in fat mass(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- change in body weight(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Change in whole blood gene expression(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Change in blood lipids(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- change in lean body mass(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Change in antioxidant status(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- biomarkers of antioxidant-rich foods(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Change in micronutrients(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- change response to stress test(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- change in plasma volume(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Change hormones(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Change in hemoglobin(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- change in blood volume(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Change in lactate(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
- Total training load(Measured one week before, during (in week 1 and 3 of the camp) and one week after the moderate altitude training camp)
研究者
Rune Blomhoff
Professor
University of Oslo