nderstanding of the role of cochlear implantation in patients with single-sided deafness and debilitating tinnitus
- Conditions
- Diseases of the ear and mastoid process
- Registration Number
- KCT0003131
- Lead Sponsor
- Asan Medical Center
- Brief Summary
Total 10 patients were recruited in this study. The average age of the patients was 62.4 years, and the average duration of hearing loss was 7.6 years. There were 4 right ears and 6 left ears, and tinnitus occurred on both sides in 2 patients and only in the deaf ear in the remaining patients. The average duration of tinnitus was 7.6 years, the same as that of hearing loss. In the functional gain test of cochlear implant, 46.7 dBnHL at 1 month, 42.8 dBnHL at 3 months, 41.9 dBnHL at 6 months, and 41.3 dBnHL at 12 months after surgery. Speech perception test (word recognition score) showed 33.3% at 1 month, 57.3% at 3 months, 54% at 6 months, and 56% at 12 months after surgery. It seems that speech clarity reached its maximum level from 3 months after surgery. When the loudness of tinnitus was measured in the tinnitogram, the average score was 6 before surgery, 2.5 at 1 month, 3 at 3 months, 2 at 6 months, and 2.5 at 12 months after surgery. There was a significant decrease compared to preoperative score, but there was no significant difference according to the postoperative period. The K-HHIE questionnaire score was 62.5 points before surgery, 54.3 points at 1 month, 40.3 points at 3 months, 38.5 points at 6 months, and 38.6 points at 12 months after surgery. The score was decreased after cochlear implantation, especially after 3months after surgery. In the THI questionnaire, when the cochlear implant was turned off, the average score was 76 before surgery, 63.6 at 1 month, 48.4 at 3 months, 37.6 at 6 months, and 34.8 points at 12 months after surgery. When the device was turned on, the score was 48 at 1 month, 26.4 at 3 months, 23.2 at 6 months, and 32.4 at 12 months after surgery. At 1 month, 3 months, and 6 months after surgery, tinnitus improved more when the device was turned on than when it was turned off. Loudness, distress, and perception of tinnitus were evaluated through the VAS scale. When the device was turned off, the average score was 8.3 before surgery, 6 at 1 month, 7.4 at 3 months, 4.4 at 6 months, and 4.3 at 12 months after surgery. When the device was turned on, 4.2 at 1 month, 4.7 at 3 months, 2.0 at 6 months, and 2.4 at 12 months after surgery. Tinnitus was significantly improved after cochlear implant, when evaluated through various questionnaires. It tended to have a better tinnitus improvement after more than 3 months rather than immediately after surgery. Also, the effect was better when the cochlear implant was turned on, than when it was turned off.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 10
Of the 19-80 year-old patients with severe to profound unilateral hearing loss with severe chronic tinnitus, the patients satisfying all of the following five criteria will be selected.
1. Adult patients over 19 years of age who have severe tinnitus at least 6 months and unilateral hearing loss
2. Patients who understand cochlear implants and voluntarily decide to participate in this study
3. Patients who do not have a disability to participate in follow-up for 1 year after participating in the study
4. Patients who voluntarily agreed to the study and signed the agreement
5. Patients who were judged to be capable of cochlear implantation on temporal bone CT
1. Patients who can not voluntarily consent
2. Patients who are in poor condition under general anesthesia
3. Patients who judged that it is difficult to restore hearing by cochlear implantation on imaging study
4. Patients who judged that he/she cannot undergo cochlear implant on imaging study
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method questionnaire on changes in tinnitus before and after cochlear implantation
- Secondary Outcome Measures
Name Time Method Pure tone audiometry;Speech audiometry;Tinnitogram (T-gram);Hearing in noise test (HINT);Temporal bone CT;quantitative electroencephalography (qEEG);T-level/C-level;resting-state fluorodeoxyglucose positron emission tomography (rs-FDG-PET);Speech evaluation