SCALE UP: Sustainable model for Cardiovascular health by Adjusting Lifestyle and treatment with Economic perspective in settings of Urban Poverty - Development, implementation and evaluation of a comprehensive intervention package for primary prevention of cardiovascular diseases in the slums of Nairobi
Not Applicable
Completed
- Conditions
- Cardiovascular diseasesCirculatory System
- Registration Number
- ISRCTN84424579
- Lead Sponsor
- Amsterdam Institute for Global Health and Development (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 8390
Inclusion Criteria
All adults aged 35 years and above living in the slums of Korogocho and Viwandani who give informed consent participate in the study
Exclusion Criteria
1. Pregnant women
2. Persons with undiagnosed CVD such as stroke (including secondary hypertension)
3. All those unable to provide informed consent such as the mentally incapacitated
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. The change in the proportion of the study populations (intervention and control slums) that are at moderate or high risk of CVD (defined as >10% risk of developing cardiovascular event in the next five years) <br>2. The change in mean systolic blood pressure in the study populations (intervention and control slums)<br>3. The change in mean systolic blood pressure among patients attending the local clinic (intervention slum only)<br>4. The net cost of the intervention model per disability-adjusted life year gained (intervention slum only)
- Secondary Outcome Measures
Name Time Method 1. Prevalence of hypertension in the intervention and control slums<br>2. Proportion of hypertensive respondents who were aware of their condition in the intervention and control slums<br>3. Proportion of hypertensive respondents who were aware of their condition and on treatment in the intervention and control slums<br>4. Proportion of hypertensive respondents who were on treatment and whose blood pressure was under control in the intervention and control slums<br>5. Proportion of patients attending the local clinic in the intervention slum who blood pressure was under control<br>6. Proportion of high risk patients who sought first time treatment after screening and referral<br>7. Prevalence of behavioural CVD risk factors: smoking, physical exercise, diet and alcohol intake in the intervention and control slums