NCT05321212已完成不适用
Efficacy (Systemic and Cerebral) and Safety of PEMbrolizumab PD-L1-positive (More Than 50% of Tumor Cells), Advanced Non-small-cell Lung Cancer : A Study of Real Life in Brittany .
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 108
- 试验地点
- 2
- 主要终点
- progression free survival with pembrolizumab
研究概览
简要总结
This study was a French multicentric cross-sectional study retrospectively of 108 consecutive advanced NSCLC patients with a PD-L1 TPS ≥50% and without EGFR/ALK aberrations treated by pembrolizumab in first line.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •histologically or cytologically confirmed NSCLC PD- L1 TPS ≥ 50% stage III and IV WHO performance status of 0, 1 or 2 adequate organ function
排除标准
- •previous EGFR or ALK aberrations positive test for hepatitis B or C virus indicating acute or chronic infection known history of testing positive for human immunodeficiency virus (HIV) severe, uncontrolled autoimmune disease.
结局指标
主要结局
progression free survival with pembrolizumab
时间窗: time from initiation of pembrolizumab to the date of disease progression or death ( 20 months)
time from initiation of pembrolizumab to the date of disease progression or death
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
1 期
Use of Mesenchymal Stem Cells (MSCs) Differentiated Into Neural Stem Cells (NSCs) in People With Parkinson's (PD).Parkinson DiseaseNCT03684122University of Jordan10
Enrolling By Invitation
不适用
Clinical Effectiveness of PEMF as a Treatment Adjunct to Eccentric Exercise for Achilles TendinopathyAchilles TendinopathyNCT05316961Chinese University of Hong Kong54
已完成
2 期
Study of the Safety, Tolerability and Pharmacokinetics of 1 Mg/Eye and 3 Mg/Eye Pegaptanib Sodium in Patients With Exudative Age-Related Macular Degeneration (AMD)Age-Related Macular DegenerationNCT00215670Eyetech Pharmaceuticals125
Unknown
3 期
A Extension Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance ( EMPIRE-02 )Insulin Resistance - Type AInsulin Resistance - Type BLipoatrophic Diabetes MellitusInsulin Resistance SyndromeNCT04221152Kobe University8
已完成
不适用
Proof of Concept Study of PEMF (Pulsed Electromagnetic Field) Therapy in Subjects With Osteoarthritis of the KneeOsteoarthritis, KneeNCT02696083Regenesis Biomedical, Inc.19