Strength training and non-invasive brain stimulation to improve walking and balance in Parkinson's disease

Not Applicable

Completed

• Conditions: Parkinson's Disease; Neurological - Parkinson's disease

• Registration Number: ACTRN12615001241527
• Lead Sponsor: Deakin University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-12
• Study Completion: 2018-06-01
• Last Update Posted: 10 February 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

1) Diagnosed with Parkinson's disease by an independent neurologist.
2) Moderate to severe motor symptoms (score of 2.5 or greater on the Hoehn and Yahr scale).
3) Stable drug regime.
4) History of 1 or more falls in the last 24 months

Exclusion Criteria

1) Presence of other neurological or brain related conditions, such as Alzheimer's disease, stroke, or epilepsy.
2) Cardiac pacemaker, deep brain stimulator, or other implanted medical device
3) Currently undertaking physical therapy or structured exercise program for the lower body.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Balance, assessed with postural sway on portable force plate[Baseline, 3 weeks, 6 weeks and 9 weeks following the commencement of the intervention];Gait speed, assessed with zeno gait analysis walkway[Baseline, 3 weeks, 6 weeks and 9 weeks following the commencement of the intervention];Corticopsinal excitability of the Tibialis Anterior muscle assessed with transcranial magnetic stimulaiton[Baseline, 3 weeks, 6 weeks and 9 weeks following the commencement of the intervention]