NCT02043912已完成不适用
Drug Interactions With Risk of QT-prolongation in a General Hospital: an Epidemiological Point Prevalence Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- KU Leuven
- 入组人数
- 222
- 试验地点
- 1
- 主要终点
- QTc-interval (corrected for heart rate)
研究概览
简要总结
In this epidemiological point prevalence study, medication profiles of patients with haloperidol treatment will be checked for drug interactions with risk of QT-prolongation. Additional clinical risk factors for developing QT-prolongation and safety measurements will be documented.
详细描述
Study design: epidemiological point prevalence study
Target population: Patients with haloperidol treatment
The following aspects will be investigated:
- The medication profiles will be checked for drug interactions with risk of QT-prolongation.
- Clinical risk factors for developing QT-prolongation (gender, age, (history of) cardiovascular disease, comorbidity,...) and lab results will be collected.
- Safety measurements (e.g. ECG) will be documented.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •treatment with haloperidol (started in the hospital)
排除标准
- •age < 18 years
研究组 & 干预措施
patients treated with haloperidol
干预措施: Haloperidol (Drug)
结局指标
主要结局
QTc-interval (corrected for heart rate)
时间窗: maximum one year before inclusion / one week after inclusion
次要结局
- number of drug interactions (with risk of QT-prolongation)(one week before/after inclusion)
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Risk of QT-prolongation and Torsade de Pointes in Patients Treated With Acute Medication in a University HospitalQT-prolongationDeliriumNCT02068170KU Leuven178
招募中
4 期
Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and SurgeryEKG-QT ProlongationNCT03893734NorthShore University HealthSystem140
已完成
3 期
Quetiapine Prolong, Escitalopram and Hypothalamic-pituitary-adrenocortical (HPA) Axis Activity in Depressed PatientsMajor DepressionNCT00953108Ludwig-Maximilians - University of Munich60
已完成
不适用
A Pharmacovigilance Study of Torsade de PointesTorsades de Pointe Caused by DrugNCT04293432University of Peshawar6,670
已完成
2 期
Evaluation of Drug-drug Interaction Between LCZ696 and Sildenafil in Subjects With Mild to Moderate HypertensionMild to Moderate HypertensionNCT01601470Novartis Pharmaceuticals28