Repetitive Transcranial Magnetic stimulation to the inferior parietal lobule in task specific focal hand dystonia;A crossover;sham-control ,blinded outcome assessment study - NI

Indian Council of Medical Research0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年4月29日

试验速览

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•Inclusion criteria-Patients meeting all of the following criteria will be
•included in the study: a) Diagnosis of isolated, task specific focal hand dystonia as per MDS consensus update on phenomenology and classification of dystonia1 by 2 independent movement disorder specialists.b) Age 18-60 years2 .c) Not received BONT injections in the past 4 months.d) No localscalp infections/ wounds
•e) Able to give informed consent.

•.3. Exclusion criteria
•Participants meeting any of the following the criteria will be
•excluded from the study a) History of brain tumour, stroke,
•traumatic brain injury, epilepsy or seizure in lifetime.
•b) History of major depression, psychosis
•c) Implanted pacemaker, intracardiac lines, pumps or
•stimulators, or metallic foreign bodies inside the eye or
•skull. (Dental fillings and braces are allowed)
•d) Pregnancy (negative UPT in 2 weeks)
•Age and gender matched Healthy volunteers, with no known neurological complaints will be included for validation of fMRI, electrophysiology and kinematic protocols.

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