NCT02303015已完成不适用
Toxicity Attributed to Genetic Polymorphisms in Testicular Germ Cell Tumor Survivors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 430
- 试验地点
- 1
- 主要终点
- Renal toxicity (Identify genetic variations predicting renal toxicity)
研究概览
简要总结
The purpose of this study is to identify genetic variations in survivors of testicular cancer and connect these variations to differences in risks of late effects.
详细描述
Identification of late-effects through questionnaires and linkage to national registries. DNA samples will be gathered through buccal swabs or saliva kits and analysed with whole exome-sequencing.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Danish citizen
- •Diagnosed with germ cell cancer from 1984 to 2007
- •Treated initially at a Danish hospital
- •Treated with standard treatment regimens.
排除标准
- •Treated initially at a foreign hospital
结局指标
主要结局
Renal toxicity (Identify genetic variations predicting renal toxicity)
时间窗: 1 year
Identify genetic variations predicting renal toxicity.
次要结局
未报告次要终点
研究者
Gedske Daugaard
Professor M.D. DMSc
Rigshospitalet, Denmark
研究点 (1)
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