Effect of Udenafil Administration for Cerebral Blood Flow Increase

Not Applicable

Recruiting

• Conditions: Not Applicable

• Registration Number: KCT0005833
• Lead Sponsor: Jeonbuk National University Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 23 February 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

Adult males aged 55 to 65 years old
-After hearing and understanding the detailed explanation of this study, the subject voluntarily decides to participate in the study and gives written consent
-When the MMSE score is taken into account of age, gender, and education level, it is at a normal level of mean-1SD or higher.
-Those who are willing to cooperate with this study and complete all phases of clinical trials, and who are practically viable

Exclusion Criteria

1. If you have a history of stroke, myocardial infarction, or CABG surgery within the past 6 months
2. Has a history of cardiac failure, unstable angina, or life-threatening arrhythmia within the last 6 months
3. If you have uncontrolled diabetes
4. If you have proliferative diabetic retinopathy
5. Spinal cord injury, radical prostatectomy and radical pelvic surgery
6. If you have hypotension of less than 90/50mmHg or uncontrolled hypertension of more than 170/100mmHg
7. If there is an abnormality in liver function or kidney function
8. If you have retinitis pigmentosa
9. Severe active peptic ulceration within the past year
10. If you have a blood disorder (sickle cellosis, multiple myeloma, leukemia) or bleeding disorder that may predispose to persistent erection
11. In case the researcher determines that it is unsuitable for participation in the test, such as mental disorder or continuous abuse of drugs
12. When taking Nitrates/Nitric oxide(NO) donor (ex. nitroglycerin, isosorbide mononitrate, isosorbide dinitrate, amyl nitrate/nitrite, Sodium nitroprusside)
13. If you are being treated with cancer chemotherapy
14. If you are taking anticoagulants
15. Taking drugs or foods that affect the metabolism of CYP3A4 in the liver
16. If you are taking Androgens (ex. testosterone) or anti-androgens
17. Use of other PDE-5 inhibitors (Viagra®, Levitra® and Cialis®) or other erectile dysfunction treatments for the treatment of erectile dysfunction within 2 weeks prior to trial
18. History of hypersensitivity to other PDE-5 inhibitors (Viagra®, Levitra® and Cialis®)

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified