Fluid treatment for severe infections in childre
Not Applicable
Completed
- Conditions
- septic shockfluid resuscitationInfection - Other infectious diseasesCardiovascular - Other cardiovascular diseasesRespiratory - Other respiratory disorders / diseases
- Registration Number
- ACTRN12614000824662
- Lead Sponsor
- The Royal Children's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Suspected infection (hyperthermia or hypothermia), cardiovascular compromise (tachycardia and abnormal capillary refill time or hypotension), and a clinical decision to administer a standardised fluid bolus (20ml/kg 0.9% saline).
Exclusion Criteria
Underlying structural cardiac disease, English as a second language in whom true informed consent cannot be obtained, those whose goals of therapy are non-curative.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link fluid resuscitation to improved stroke volume in paediatric sepsis?
How does fluid resuscitation compare to vasopressors in managing IVC collapsability in septic shock?
What biomarkers correlate with lung ultrasound score changes during fluid treatment in children with sepsis?
What adverse events are associated with aggressive fluid resuscitation in paediatric sepsis and how are they managed?
Are there combination therapies that enhance fluid resuscitation outcomes in severe infectious diseases?