Vitamin D and Type 2 Diabetes - a Cross Sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 主要终点
- Vitamin D status and its association with inflammation, glycemic control, lipids and blood pressure.
研究概览
简要总结
The purpose of the study is to describe vitamin D status among patients with type 2 diabetes and to determine the association between serum 25-hydroxyvitamin D and glycemic control, markers of inflammation and blood pressure
详细描述
It has been estimated that 1 billion people worldwide have vitamin D deficiency or insufficiency. It is well known that vitamin D deficiency causes osteoporosis, increases the risk of fracture and causes muscle weakness. But there is now evidence that calcium malnutrition and hypovitaminosis D are predisposing conditions for various common chronic diseases such as malignancies (particularly colon, breast and prostate) chronic inflammatory and autoimmune disease (inflammatory bowel disease, multiple sclerosis) as well as metabolic disorders (metabolic syndrome, hypertension).
It has also been reported that vitamin D deficiency may predispose to glucose intolerance, altered insulin secretion and type 2 diabetes mellitus.
The purpose of this study is to determine vitamin D status among type 2 diabetics in our outpatient clinic and examine the relationship between vitamin D status , calcium and phosphorous metabolism, inflammatory markers, glycemic control, blood pressure and lipid profile.
Moreover the patients are asked to answer a questionnaire regarding lifestyle, exercise, sun exposure and food intake.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 90 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Type 2 diabetes mellitus
- •Patients of Danish extraction
- •Written consent
排除标准
- •Renal failure (Urea > 12 mmol/l)
- •Age < 18 years
- •malabsorption
结局指标
主要结局
Vitamin D status and its association with inflammation, glycemic control, lipids and blood pressure.
时间窗: December 08
次要结局
- Lifestyle (exercise, sun exposure, food intake)(December 08)
