ACTRN12618001240235撤回3 期
For people with Dupuytren's disease of the hand, is treatment with percutaneous fasciotomy as effective as injectable collagenase in improving functionality and fixed flexure angles.
aunceston General Hospital0 个研究点目标入组 100 人开始时间: 2018年7月23日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 撤回
- 发起方
- 入组人数
- 100
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Dupuytren’s disease with contracture (20-100 degrees Metacarpo-phalyngeal (MCP) joint or 20-80 at the proximal interphalyngeal (PIP) joint.)
- •Consulting clinician deems it appropriate management for the patient to have one or other of the fasciotomy procedures
- •No previous treatment within 90 days
- •Able to provide informed consent; age 18 years and older
排除标准
- •Bleeding disorder, blood thinning treatment (except aspirin 150mg/day)
- •Allergy to collagenase ; pregnancy, breast feeding; neuromuscular disorders
- •Administration of tetracyclines, antracyclines or anthraquinones in the past 14 days (these meds inhibit matrix metalloproteinase-mediate collagen degradation at suprapharmacological concentrations in vitro).
研究者
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