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Clinical Trial On Testing Efficacy & Safety For 2 Siddha Formulations For Functional Constipatio

Phase 2
Conditions
Health Condition 1: K590- Constipation
Registration Number
CTRI/2019/02/017831
Lead Sponsor
Central Council For Research In Siddha
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Age range between 19 â?? 65 years

2.People meeting the Rome III Diagnostic Criteria

3.Must include two or more of the following:

a.Straining during at least 25% of defecation

b.Lumpy or hard stools in at least 25 % of defecation

c.Sensation of incomplete evacuation for at least 25% of defecation

d.Sensation of ano-rectal obstruction/blockage for at least 25% of defecation

e.Manual maneuvers to facilitate at least 25% of defecation (e.g., digital evacuation, support of the pelvic floor)

f.Fewer than three defecation per week

4.Loose stools are rarely present without the use of laxatives

5.Insufficient criteria for irritable bowel syndrome

6.Patient with stool form score ranging 1-2 Bristol Stool Form Scale

7.People willing to undergo intervention and cooperate with investigations.

Exclusion Criteria

1.Patients on Chronic laxative medication ( > 60 day)

2.Medications known to cause constipation

a.Opioid Analgesics

b.Antidepressants

c.Anti Convulsants

d.Aluminium containing Antacids

3.Functional gastro intestinal disorders

a.Belching Disorders

b.Irritable Bowel Syndrome

c.Haemorrhoids

4.H/O Abdominal Surgery in the past 1 year

5.H/O Ano-Rectal Surgery in the past 1 year

6.H/O any Structural Abnormalities in GI tract

7.H/O Chronic DM Medications

8.H/O Chronic HT Medications

9.H/O Renal Dysfunction (KFT Abnormalities)

10.H/O Liver Dysfunction (LFT Abnormalities)

11.H/O Thyroid Disorders and Medications

12.Smoking and alcohol consumption

13.Drug withdrawal within past 6 months

14.H/O Neurological Problems

a.Multiple Sclerosis

b.Parkinsonâ??s Disease

c.Paraplegia

d.Sacral Nerve Damage

15.Lactating women

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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