Effect of supplementation of vitamin and the serum and milk of breastfeeding wome

Not Applicable

Recruiting

• Conditions: Vitamin E; Lactation; Deficiency in vitamin E.; C18.654.521.500.133.841; D03.383.663.283.909; G08.686.523

• Registration Number: RBR-38nfg2
• Lead Sponsor: Departamento de Bioquímica da Universidade Federal do Rio Grande do Norte

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-07-24
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women 30 to 60 days postpartum who are in the waiting room of the ambulatory care and breastfeeding their child; residents of Natal, state of Rio Grande do Norte; without diagnosis of diseases such as hypertension, diabetes, neoplasias, cardiopathies, diseases of the gastrointestinal and hepatic tract, syphilis, HIV positive; non-smokers and who had deliveries with a single concept and without malformation.

Exclusion Criteria

Women who do not have milk; illicit drug users who use vitamin E vitamin supplements.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
EExpected outcome: Increased alpha-tocopherol levels in maternal blood and milk following vitamin E supplementation. To determine the expected outcome, the amount of alpha-tocopherol in blood and breast milk will be assessed before and after supplementation. Statistical tools will be used to compare the two groups studied. Vitamin E supplementation is expected to contribute to the increase of this micronutrient in serum and mature milk of infants, based on the analysis of serum alpha-tocopherol and breast milk using the High Performance Liquid Chromatography technique (HPLC).<br>

Secondary Outcome Measures

Name	Time	Method
Expected outcome: Maternal factors that may contribute to the increase of vitamin E in supplemented infants. For this finding it is necessary to evaluate the socioeconomic level of the mothers, diet and evaluation of circulating lipoproteins. To verify the expected outcome, statistical tools will be used to verify if such characteristics may influence the effect of vitamin E supplementation.