The Relationship Between Oxytocin Level and Postpartum Depression

Completed

• Conditions: Prenatal Stress; Postpartum Depression; Oxytocin Deficiency
• Interventions: Diagnostic Test: Salivary test

• Registration Number: NCT04427410
• Lead Sponsor: Cukurova University

Brief Summary

There are studies in the literature that associate oxytocin level with postpartum depression. This study was carried out to investigate the relationship between oxytocin levels measured during pregnancy and postpartum depression symptoms.

Detailed Description

Introduction and purpose: There are studies in the literature that associate oxytocin level with postpartum depression. This study was carried out to investigate the relationship between oxytocin levels measured during pregnancy and postpartum depression symptoms.

Method: The study was conducted with 70 women who met the research criteria. Data collection was done in two interviews. The first meeting is 30-38 at the week of gestation, the second interview is 4-12 at the week of postpartum. It was done between weeks. In each interview, a data collection form was applied first and then a saliva sample was taken. Data collection form; The questions prepared by the researchers consisted of the Edinburgh Postnatal Depression Scale (EPDS) and Beck Depression Inventory (BDI). The data were analyzed using SPSS 22.0 program and the significance value was taken as p \<0.05.

Study Timeline

• Study Start: 2019-07-20
• Primary Completion: 2019-10-20
• Study Completion: 2020-02-20
• Status Verified: 2020-06
• Study First Submitted: 2020-06-08
• Study First Submitted QC: 2020-06-10
• Last Update Submitted: 2020-06-10
• Study First Posted: 2020-06-11
• Last Update Posted: 2020-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

• 18 years of age or older, and having a pregnancy of 30 weeks or more

Exclusion Criteria

• previous mental illness history, miscarriage or stillbirth history, multiple pregnancy, fetal malformation, antidepressant or anxiolytic drug use, existing chronic disease,preterm labor is the development of maternal or neonatal complications at birth, hospitalization in the neonatal intensive care unit or congenital disease.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
pregnancy	Salivary test	-
postpartum	Salivary test	-

Primary Outcome Measures

Name	Time	Method
Oxytocin levels	3-6 month	Oxytocin levels in pregnancy and postpartum period

Trial Locations

Locations (1)

Cukurova University; 🇹🇷 Adana, Saricam, Turkey