ITMCTR2000002922尚未招募4 期
Epigenetic regulation of qi-deficiency and blood-stasis syndrome in conescence of myocardial infarction by supplementing Qi-Xu Xue-Yu zhen based on CDKN2A pathway
The second affiliated hospital of tianjin university of traditional Chinese medicine0 个研究点开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional study
入排标准
- 年龄范围
- 35 至 70（—）
- 性别
- All
入选标准
- •1. aged 35-70 years old;
- •2. patients with acute myocardial infarction, 15 days to 3 months after clinical diagnosis and treatment;
- •3. the subject's condition was stable within 15 days;
- •4. TCM syndrome type is identified as qi deficiency and blood stasis:
- •(1) main symptoms: chest tightness, chest pain 2) secondary symptoms (blood stasis: purple and dark lips, complexion or claw plate;The tongue is purple or dark or has petechiae or ecchymosis;The veins under the tongue are coarse; Pulse acerbity or sink string, string late;
- •(2) gas deficiency: palpitations and shortness of breath; God languishes; Easy to sweat, moving is aggravated;Complexion white; Tongue is weak; Teeth marks on the side of tongue; Weak pulse;
- •5. voluntarily sign the informed consent;
- •6. healthy group: aged 35 to 70 years old; Did not take any drugs or participate in other clinical trials within 3 months; no coronary heart disease, metabolic disease and other diseases; voluntary signing of informed consent.
排除标准
- •(1) patients with congenital heart disease, heart valve disease, aneurysm, allergic constitution, metabolic diseases (except diabetes), severe infection, severe liver and kidney dysfunction, and a history of cerebrovascular disease;(2) women of child-bearing age who have planned to become pregnant within 2 years (defined as all women of child-bearing age who are physically capable of becoming pregnant) and women who have become pregnant;
- •(3) those who have participated in any drug clinical trial within the first 3 months;
- •(4) the researcher judged that the survival of the patients should not exceed 6 months;
- •(5) patients with severe neurological diseases (alzheimer's disease, progressive stage of Parkinson's disease), lower limb disability or deaf-mute;
- •(6) patients with a previous history of tumor or current tumor, or confirmed by pathological examination to have precancerous lesions;
- •(7) patients who have been found to have a malignant mass by examination (physical examination, X-ray examination or b-ultrasound examination or other means), or who have been found to have endocrine activity, hyperplasia glands or adenoma affecting heart or endocrine function, such as pheochromocytoma, goiters, etc.;
- •(8) in the judgment of the investigator, the patient is unable to complete the study or comply with the requirements of the study (due to management reasons or other special reasons);
- •(9) healthy subjects: pregnant women; Drug use in the first 3 months; participated in other clinical trials; In the judgment of the investigator, the patient is unable to complete the study or comply with the requirements of the study (due to management reasons or other special reasons).
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