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BMI and Lymph Node Count in Colorectal Cancer

Completed
Conditions
The Aim of This Study is to Determine the Influence of BMI and Lymph Node Status on OS in CRC Patients in the Long Term
Registration Number
NCT06334926
Lead Sponsor
Klinikum Floridsdorf
Brief Summary

Background and aim: Colorectal Cancer (CRC) is one of the most frequent cancer entities in the western world. It is known that obesity is one of the major risk factors for CRC. In contrast, mild obesity seems to have a positive effect on postoperative outcome, which is known as the "obesity paradox". Also, the number of resected lymph nodes (LN) during surgery is very important for correct staging. The aim of the present project is to evaluate the impact of BMI and LN-yield on long term overall survival (OS) of CRC patients treated with curative intent.

Methods: Patients treated for CRC between 1998 and 2011 at the Klinik Favoriten in Vienna, Austria were analyzed in this retrospective single-center cohort analysis concerning OS.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1192
Inclusion Criteria
  • colorectal carcinoma
  • treated at the Klinik Favoriten between 1998 and 2011
  • elective or acute surgical setting
  • curative intent
  • older than 18 years
Exclusion Criteria
  • other carcinoma (anal, metastases, ...)
  • treated before 1998 or after 2011
  • palliative intent
  • younger than 18 years

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
overall survivalmedian follow up of 11.3 years

The aim of the present project is to evaluate the impact of BMI and LN-yield on long term overall survival (OS) of CRC patients treated with curative intent.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Klinik Floridsdorf

🇦🇹

Wien, Austria

Klinik Floridsdorf
🇦🇹Wien, Austria

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