Prediction of Survival in Colorectal Cancer Patients on the Basis of Body Mass Index and Lymph Node Yield - a Retrospective Single Center Cohort Analysis Over a Quarter of a Century
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,192
- 试验地点
- 1
- 主要终点
- overall survival
研究概览
简要总结
Background and aim: Colorectal Cancer (CRC) is one of the most frequent cancer entities in the western world. It is known that obesity is one of the major risk factors for CRC. In contrast, mild obesity seems to have a positive effect on postoperative outcome, which is known as the "obesity paradox". Also, the number of resected lymph nodes (LN) during surgery is very important for correct staging. The aim of the present project is to evaluate the impact of BMI and LN-yield on long term overall survival (OS) of CRC patients treated with curative intent.
Methods: Patients treated for CRC between 1998 and 2011 at the Klinik Favoriten in Vienna, Austria were analyzed in this retrospective single-center cohort analysis concerning OS.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •colorectal carcinoma
- •treated at the Klinik Favoriten between 1998 and 2011
- •elective or acute surgical setting
- •curative intent
- •older than 18 years
排除标准
- •other carcinoma (anal, metastases, ...)
- •treated before 1998 or after 2011
- •palliative intent
- •younger than 18 years
结局指标
主要结局
overall survival
时间窗: median follow up of 11.3 years
The aim of the present project is to evaluate the impact of BMI and LN-yield on long term overall survival (OS) of CRC patients treated with curative intent.
次要结局
未报告次要终点
研究者
Dr. Tamara Braunschmid
MD
Klinikum Floridsdorf