Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment
- Conditions
- Acute Myocardial InfarctionHeart Failure
- Registration Number
- NCT03297164
- Lead Sponsor
- Harbin Medical University
- Brief Summary
The main purpose of this study is to build a multi-center, prospective and regionally representative acute myocardial infarction(AMI) cohort，and build a study platform for heart failure caused by AMI; To explore the 1 year incidence rate of heart failure after AMI given the optimized treatment and the treatment model affecting the incidence rate of heart failure, and finally to reduce the incidence rate of heart failure by 5%.
- Detailed Description
the study aim to enroll 12000 acute myocardial infartion (AMI) patients, including ST-segment elevation myocardial infarction (STEMI) and non ST-segment elevation myocardial infarction (NSETMI), Patients were divided into two groups(optimized group and un-optimized group) according to treatment models they accepted in 20 reginally representative hosptials of China. whether optimizaed or not is judged by 4 four aspects,including emergency treatment procedure, pre-infusion medication, reperfusion strategy selection, and early rehabilitation after reperfusion.Patients were followed at 1 month, 6 months and 12 months. The physical condition and clinical events(heart failure, death, re-infarction, revascularization, apoplexy, malignant arrhythmias, bleeding events, other adverse events)were collected at follow up.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 12043
- age≥18 years
- diagnosed acute myocardial infarction
- signed the informed consent form
- AMI is caused by surgery, trauma, gastrointestinal bleeding or complications of PCI;
- AMI occurred in patients who have been hospitalized for other reasons;
- patients with previous history of chronic heart failure;
- researchers judging that patient's compliance was poor and could not complete the study according to the requirements.
- life expectancy is less than 12 months;
- heart transplant patients;
- patients with tumors;
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method incidence rate of heart failure 12th month after diacharge incidence rate of heart failure of acute myocardial infarction at 12th month
- Secondary Outcome Measures
Name Time Method MACCE rate 12th month after diacharge the major adverse cardiac celebral events including death,reinfarction,
bleeding rate 12th month after diacharge the incidence rate of bleeding
severe adverse drug reactions 12th month after diacharge severe adverse drug reactions at 12th month
Trial Locations
- Locations (19)
Guangdong general hospital
🇨🇳Guangzhou, Guangdong, China
Zhongda Hospital Southeast University
🇨🇳Nanjing, Jiangsu, China
Daqing Oilfield General Hospital
🇨🇳Daqing, Heilongjiang, China
The first affiliated hospital of Guangxi medical university
🇨🇳Nanning, Guangxi, China
Second hospital of hebei medical university
🇨🇳Shijiazhuang, Hebei, China
Beijing An Zhen Hospital, Capital Medical University
🇨🇳Beijing, Beijing, China
The first affiliated hospital of Zhengzhou medical university
🇨🇳Zhengzhou, Henan, China
The Second Affiliated Hospital of Nanchang University
🇨🇳Nanchang, Jiangxi, China
the second affiliated hospital of Dalian medical university
🇨🇳Dalian, Liaoning, China
Shenyang military district general hospital of the people's liberation army
🇨🇳Shenyang, Liaoning, China
The first affiliated hospital of military medical university
🇨🇳Xi'an, Shanxi, China
Third Military Medical University
🇨🇳Chongqing, Sichuan, China
Tianjin Chest Hospital
🇨🇳Tianjing, Tianjin, China
The General Hospital of Tianjin Medical University
🇨🇳Tianjin, Tianjin, China
Peking Univerisity People'Hospital
🇨🇳Beijing, Beijing, China
Beijing Chao-Yang Hospital, Capital Medical University
🇨🇳Beijing, Beijing, China
The Second Hospital of Jilin University
🇨🇳Changchun, Jilin, China
The First Affiliated Hospital of Xinjiang Medical University
🇨🇳Urumqi, Xinjiang, China
Peking University First Hospital
🇨🇳Beijing, Beijing, China