One Year Incidence Rate of Heart Failure After Acute Myocardial Infarction With Optimal Treatment-A Prospective,Multicenter,Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Myocardial Infarction
- Sponsor
- Harbin Medical University
- Enrollment
- 12043
- Locations
- 19
- Primary Endpoint
- incidence rate of heart failure
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
The main purpose of this study is to build a multi-center, prospective and regionally representative acute myocardial infarction(AMI) cohort，and build a study platform for heart failure caused by AMI; To explore the 1 year incidence rate of heart failure after AMI given the optimized treatment and the treatment model affecting the incidence rate of heart failure, and finally to reduce the incidence rate of heart failure by 5%.
Detailed Description
the study aim to enroll 12000 acute myocardial infartion (AMI) patients, including ST-segment elevation myocardial infarction (STEMI) and non ST-segment elevation myocardial infarction (NSETMI), Patients were divided into two groups(optimized group and un-optimized group) according to treatment models they accepted in 20 reginally representative hosptials of China. whether optimizaed or not is judged by 4 four aspects,including emergency treatment procedure, pre-infusion medication, reperfusion strategy selection, and early rehabilitation after reperfusion.Patients were followed at 1 month, 6 months and 12 months. The physical condition and clinical events(heart failure, death, re-infarction, revascularization, apoplexy, malignant arrhythmias, bleeding events, other adverse events)were collected at follow up.
Investigators
Yu Bo
director
Harbin Medical University
Eligibility Criteria
Inclusion Criteria
- •age≥18 years
- •diagnosed acute myocardial infarction
- •signed the informed consent form
Exclusion Criteria
- •AMI is caused by surgery, trauma, gastrointestinal bleeding or complications of PCI;
- •AMI occurred in patients who have been hospitalized for other reasons;
- •patients with previous history of chronic heart failure;
- •researchers judging that patient's compliance was poor and could not complete the study according to the requirements.
- •life expectancy is less than 12 months;
- •heart transplant patients;
- •patients with tumors;
Outcomes
Primary Outcomes
incidence rate of heart failure
Time Frame: 12th month after diacharge
incidence rate of heart failure of acute myocardial infarction at 12th month
Secondary Outcomes
- MACCE rate(12th month after diacharge)
- bleeding rate(12th month after diacharge)
- severe adverse drug reactions(12th month after diacharge)