Validation of the Chinese Version of Oxford Depression Questionnaire

Completed

• Conditions: Mood Disorders; Emotional Blunting
• Interventions: Diagnostic Test: Oxford Depression Questionnaire (ODQ)

• Registration Number: NCT05535270
• Lead Sponsor: First Affiliated Hospital of Zhejiang University

Brief Summary

Mood disorders are a group of psychiatric disorders that can affect a person's mood, energy, and motivation. Emotional blunting has been observed in clinical practice in patients with mood disorders. Emotional blunting has a negative impact on patients' overall treatment and leads to poorer adherence. The Oxford Depression Questionnaire (ODQ) is a measuring instrument of emotional blunting. The ODQ is expected to be a scientifically valid tool for detecting emotional blunting. The ODQ has high construct validity and internal reliability. However, no scientific validity studies have been conducted on ODQ in Chinese population. Therefore, this study is intended to investigate the reliability and validity of the ODQ in Chinese patients with mood disorders.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-01
• Study First Submitted: 2022-09-06
• Study First Submitted QC: 2022-09-08
• Study First Posted: 2022-09-10
• Primary Completion: 2023-06-01
• Study Completion: 2023-06-30
• Status Verified: 2023-09
• Last Update Submitted: 2023-09-14
• Last Update Posted: 2023-09-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 272

Inclusion Criteria

1. both biological parents were Han Chinese; 2) currently diagnosed with major depressive disorder or bipolar disorder according to the Mini International Neuropsychiatric Interview for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition; 3) aged 13-65 years; 4) can complete the self-assessment questionnaires.

Exclusion Criteria

1. currently diagnosed with neurological diseases or other major psychiatric disorders, e.g., schizophrenia, cognitive impairment, substance abuse; 2) diagnosed with severe somatic illnesses, such as diabetes and cardiovascular diseases;

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Healthy Controls	Oxford Depression Questionnaire (ODQ)	The participants completed a demographic questionnaire, Patient Health Questionnaire - 9(PHQ-9), and the first two sections of Oxford Depression Questionnaire (ODQ-20).
Mood Disorder patients	Oxford Depression Questionnaire (ODQ)	The participants completed a demographic questionnaire, the self-report Oxford Depression Questionnaire (ODQ-C), the Beck Depression Inventory-II(BDI-II), and the Montgomery-Asberg Depression Rating Scale (MADRS).

Primary Outcome Measures

Name	Time	Method
Oxford Depression Questionnaire (ODQ)	baseline	To analyze reliability and validity of the ODQ.

Secondary Outcome Measures

Name	Time	Method
Beck Depression Inventory-II (BDI-II)	baseline	To analyze criterion validity of the Chinese version of the ODQ
Montgomery-Asberg Depression Rating Scale (MADRS)	baseline	To analyze correlation with ODQ
Oxford Depression Questionnaire (ODQ)	2 weeks after baseline	To analyze Test-retest reliability coefficients of the ODQ.

Trial Locations

Locations (1)

Department of Psychiatry, First Affiliated Hospital of Zhejiang University; 🇨🇳 Hangzhou, Zhejiang, China