To study the changes in the endotracheal tube cuff pressure during abdominal surgery.

Completed

• Conditions: Malignant neoplasm of prostate, (2) ICD-10 Condition: C569||Malignant neoplasm of unspecifiedovary, (3) ICD-10 Condition: C55||Malignant neoplasm of uterus, partunspecified,

• Registration Number: CTRI/2019/05/018906
• Lead Sponsor: Rajiv Gandhi Cancer Institute And Research Center

Brief Summary

This is a hospital-based, prospective, observational, cohort study comparing the changes in the endotracheal tube cuff pressure in 60 cases of abdominal surgeries requiring pneumoperitoneum with 60 cases of open abdominal surgeries. Our primary objective is to study how pneumoperitoneum effects endotracheal tube cuff pressure and secondary objective is to correlate the changes in endotracheal tube cuff pressure with BMI and airway pressure, at different different time points during the surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-05-15
• Study Completion: 2020-07-20
• Last Update Posted: 2021-04-20

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• ASA GRADE I & II.
• DURATION OF SURGERY MORE THAN 2 HOURS.
• ABDOMINAL SURGERY REQUIRING LITHOTOMY POSITION.

Exclusion Criteria

• ASA Grade III & IV.
• Respiratory disorders.
• N2O Administration.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in endotracheal tube cuff pressure during abdominal surgery with pneumoperitoneum.	T0 After intubation,T1 Before lithotomy, T2 After lithotomy, T3 Before pneumoperitoneum, T4 Just after pneumoperitoneum,T5 5minutes after pneumoperitoneum, T6a 30mins, T6b 60mins, T6C 90mins, T6d 120mins, T6e 150mins,T6f 180mins,T7 Before the release of pneumoperitoneum, T8 After the release of pneumoperitoneum, T9 Supine position, T10 Before extubation.

Secondary Outcome Measures

Name	Time	Method
Changes in endotracheal tube cuff pressure during open abdominal surgery.	T0 After intubation,T1 Before lithotomy, T2 After lithotomy, T3 Before incision, T4 Just after incision,T5 5minutes after incision, T6a 30mins, T6b 60mins, T6C 90mins, T6d 120mins, T6e 150mins,T6f 180mins,T7 Before the closure, T8 After the closure, T9 Supine position, T10 Before extubation.

Trial Locations

Locations (1)

Rajiv Gandhi Cancer Institute; 🇮🇳 West, DELHI, India

Rajiv Gandhi Cancer Institute

🇮🇳West, DELHI, India

Dr Divya meghana

Principal investigator

7981017162

ndmeghana@gmail.com