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临床试验/CTRI/2018/05/013712
CTRI/2018/05/013712已完成不适用

Comparison Of Postoperative Analgesic Efficacy Between Surgical Wound Site Infiltration and Ultrasound Guided Ilioinguinal Iliohypogastric Nerve Block Following Inguinal Hernia Repair Under Spinal Anaesthesia

Department of Anaesthesiology1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2015年1月2日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
50
试验地点
1
主要终点
2.comparison of time to first request of morphine in hours

研究概览

简要总结

Background: Ultrasound guided ilioinguinal iliohypogastric nerve block has been reported to provide effective analgesia after lower abdominal surgeries but there are only very few data comparing it with surgical wound site infiltration with local anaesthesia in patients undergoing inguinal hernia repair under spinal anaesthesia

Objectives: to compare the efficacy of Ultrasound guided ilioinguinal nerve block with surgical wound site infiltration for postoperative analgesia in inguinal hernia repair under spinal anaesthesia

Method: prospective cohort study comprising of 50 patients undergoing inguinal hernia repair under spinal anaesthesia and has received ultrasound guided nerve block or surgical wound site infiltration with 10 ml of 0.25% bupivacaine.Quality of analgesia was compared in terms of Visual analogue scores (VAS) at 0,0.5,1,2,4,6,12,24 hours post operatively, morphine (rescue analgesic) consumption in first 24 hrs and time to first dose of morphine. other study parameters were nausea, vomiting,sedation score measured using 4 point categorical scale and consumption of ondansetron ( rescue antiemetic).

Results: VAS scores were significantly lower in the nerve block group (p value <0.05).The morphine consumption was also significantly lower (p value<0.013) and the time to first dose of morphine was significantly longer (p value<0.0001) in the nerve block group.There was no significant difference in case of sedation nausea and vomiting and as a result the mean rescue antiemetic doses were comparable in both the groups.

Conclusion: ultrasound guided ilioinguinal iliohypogastric nerve block provided better postoperative pain control than surgical wound site infiltration for inguinal hernia repair and therefore can be recommended as a part of multimodal analgesic regimen for the same

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • ASA 1 and ASA 2 patients undergoing inguinal hernia repair under spinal anaesthesia.

排除标准

  • pregnant and lactating women history of drug allergy to bupivacaine, chronic pain bilateral inguinal hernia repair refusal to consent.

结局指标

主要结局

2.comparison of time to first request of morphine in hours

时间窗: 0,0.5,1,2,4,6,12,24 hours

3. comparison of total 24 hours consumption of morphine

时间窗: 0,0.5,1,2,4,6,12,24 hours

1. comparison of postoperative analgesia using visual analogue pain scale

时间窗: 0,0.5,1,2,4,6,12,24 hours

次要结局

  • 1. comparison of vital signs(2. comparison nausea, vomiting, sedation using the four point categorical scale in the postoperative period)

研究者

发起方
Department of Anaesthesiology
申办方类型
Private medical college

研究点 (1)

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