Oestrogen Withdrawal in Hypopituitary Women

Not Applicable

Completed

• Conditions: Hypopituitarism
• Interventions: Drug: oestrogen

• Registration Number: NCT00572390
• Lead Sponsor: University of Aarhus

Brief Summary

By exploring hormonal status in hypopituitary women during oestrogen treatment and without estrogen substitution the influence on sexhormones and organ function is estimated.

Detailed Description

38 hypopituitary women were examinined twice. During oestrogen treatment and after 1 month estrogen withdrawal. A control group of healthy women were examined once.Antropometric data and hormonal parameters were collected.

Study Timeline

• Study Start: 2001-01
• Study Completion: 2002-02
• Status Verified: 2007-12
• Study First Submitted: 2007-12-11
• Study First Submitted QC: 2007-12-12
• Last Update Submitted: 2007-12-12
• Study First Posted: 2007-12-13
• Last Update Posted: 2007-12-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 38

Inclusion Criteria

• Hypopituitarism

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
2	oestrogen	Oestrogen treatment
1	oestrogen	No oestrogen treatment

Primary Outcome Measures

Name	Time	Method
androgens, IGF-I, body composition, liver enzymes,	1 month

Secondary Outcome Measures

Name	Time	Method
Grehlin, adiponection, leptin	1 month

Trial Locations

Locations (1)

Århus Universityhospital; 🇩🇰 Århus, Denmark