The efficacy of cranberry capsules for radiation cystitis in prostate cancer patients

Phase 3

Completed

• Conditions: Cancer - Prostate; radiation cystitis; prostate cancer; Renal and Urogenital - Other renal and urogenital disorders

• Registration Number: ACTRN12615001311549
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-12-01
• Study Completion: 2019-04-15
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 110

Inclusion Criteria

All men attending the Radiation Therapy Department in Dunedin Hospital who will receive radiation therapy for prostate cancer.

Exclusion Criteria

previous RT to the pelvis
distant metastatic disease
allergy to cranberries
history of kidney stones
on warfarin medication

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Severity of non-haemorrhagic radiation cystitis as measured by RICAS, modified RTOG and the O'Leary-Sant Symptom and Problem scales for Interstitial Cystitis (IC).[RICAS, modified RTOG and IC scores will be recorded weekly from baseline till three weeks after completion of radiation treatment.]

Secondary Outcome Measures

Name	Time	Method
Sensitivity of RICAS compared to the modified RTOG and IC in measuring the severity of non-haemorrhagic radiation cystitis.[RICAS, RTOG and IC scores are recorded weekly from baseline until three weeks after completion of radiation therapy.]