Study to compare the effect of a synthetic bone graft material alone and in combination with a component of blood (platelet membrane) in bony defects associated with gum diseases
- Conditions
- Health Condition 1: null- Periodontitis (osseous defects)
- Registration Number
- CTRI/2012/07/002793
- Lead Sponsor
- SMBT DENTAL COLLEGE HOSPITA
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 20
1. Intrabony defects in maxillary and mandibular arch
2. Patients with two or more intrabony defects (Isolateral/contralateral) as well as isolated intrabony defects
3. Intrabony defects (IBD)greater than or equal to 3 mm deep [distance between alveolar crest and base of the defect on intraoral periapical radiograph (IOPA)] along with an interproximal probing depth (PD) greater than or equal to 5 mm following phase I therapy
4. Absence of overt clinical inflammation at the time of surgery
5. Adequate amounts of interdental soft tissues
6. Absence of any local anatomical limitations
7. Patient willing for surgery and ready to give written consent
1.Patients with systemic illness known to affect the outcomes of periodontal therapy, such as diabetes mellitus, cardiac diseases, platelet count less than 200,000/mm cube, or immunocompromised (e.g., HIV individuals) patients taking medications, such as corticosteroids.
2.Individuals allergic to medications
3.Pregnant or lactating women
4.Patients using tobacco in any form
5.Individuals with unacceptable oral hygiene (plaque index [PI] greater than 1.5).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Probing depth, Clinical attachment levelTimepoint: 4 months
- Secondary Outcome Measures
Name Time Method Radiographic evaluation with the help of image analysis softwareTimepoint: 4 months