Chinese Medicine Prevention and Treatment Program for Pre-clinical Rheumatoid Arthritis: An Evidence-based Evaluation Study

Not Applicable

• Conditions: Rheumatoid Arthritis

• Registration Number: ITMCTR1900002430
• Lead Sponsor: Zhejiang Chinese Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1) Patients should suffer from >=1 arthritis (joint pain with swelling) and ACPA-positive, but do not meet the classification criteria of 1987 ACR RA classification criteria nor the 2010 ACR/EULAR RA classification criteria or other RA classification criteria;
2) The duration of diseases should last 6 weeks to 6 months;
3) Patients should meet the criteria of the patent of spleen deficiency and blockage of wind and damp;
4) Patients aged 18 to 65 years;
5) Patients will be well informed and agree to participate in this study.

Exclusion Criteria

1) Patients were treated with DMARDs or hydroxychloroquine within 2 months when agreeing to participate in this study;
2) Patients were treated with glucocorticoids;
3) Patients who suffer from severe organ disease or mental illness;
4) Patients who are allergic or have contraindications to the drugs involved in the study.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
RA transition rate;

Secondary Outcome Measures

Name	Time	Method
Patent scores;Simplified disease activity index, SDAI;patient's global assessment ofdisease activity, PGA;Clinical disease activity index, CDAI;physician's global assessment of disease activity, MDGA;Visual Analogue Scale/Score, VAS;