Surgical Stress Measured by Microdialysis

Not Applicable

Completed

• Conditions: Trauma

• Registration Number: NCT01495143
• Lead Sponsor: Northern Orthopaedic Division, Denmark

Brief Summary

Paraspinal muscle damage is inevitable during conventional posterior lumbar fusion surgery. Minimal invasive surgery is postulated to result in less muscle damage and better outcome. The aim of this study is to monitor metabolic changes of the paraspinal muscle and to evaluate paraspinal muscle damage during surgery using microdialysis (MD).

Detailed Description

Posterior approach is a common and important surgical procedure for various lumbar diseases. Owing to the anatomy, the damage of paraspinal muscle is inevitable during conventional posterior lumbar fusion surgery. Degeneration and malfunction of the paraspinal muscle might associate with pain and inferior postoperative clinical outcome.

Study Timeline

• Study Start: 2007-01
• Primary Completion: 2007-12
• Study Completion: 2008-06
• Study First Submitted: 2009-12-29
• Study First Submitted QC: 2011-12-15
• Study First Posted: 2011-12-19
• Status Verified: 2014-09
• Last Update Submitted: 2014-09-12
• Last Update Posted: 2014-09-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
The glycerol concentration	Two hours	To study whether the glucerol concentration can be used to evaluate surgery related paraspinal muscle damage