Effects of transcranial direct current stimulation followed by upper body exercises on neuropathic pain in individuals with chronic spinal cord injury

Phase 2

Completed

• Conditions: chronic spinal cord injuryneuropathic pain; chronic spinal cord injury; neuropathic pain

• Registration Number: TCTR20171222001
• Lead Sponsor: ational Yang Ming University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-12-22
• Study Completion: 2019-02-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

(1) having diagnosis of SCI-associated neuropathic pain (NP), (2) having NP symptoms for more than 6 months, (3) intensity of NP greater than 4 / 10 indicated by numeric rating scale (NRS), (4) under other analgesic treatments for 3 months but not receiving satisfied effect, and (5) willing and consent to participate the study.

Exclusion Criteria

(1) unstable medical condition, (2) unable to participate in exercise programs due to other diseases or lesions, (3) had or has drug addiction problems, (4) participating in other clinical trial in previous month, (5) history of epilepsy, underwent brain surgery, meningitis, encephalitis, and intracranial space occupied lesion, (6) has a cardiac pacemaker, (7) undergoing pregnancy or lactation, (8) any kind of metal or other implant in brain or head, (9) pathological changes over skin of stimulation sites

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pain intensity before (pre-test), immediately after the test (post-test), and 4-week follow-up (follow-up test). numeric rating scale (NRS)

Secondary Outcome Measures

Name	Time	Method
character of NP before (pre-test), immediately after the test (post-test), and 4-week follow-up (follow-up test). Neuropathic Pain Symptom Inventory (NPSI) ,Self-rating change of pain immediately after the test (post-test), and 4-week follow-up (follow-up test). patient global impression of change (PGIC),Quality of life before (pre-test), immediately after the test (post-test), and 4-week follow-up (follow-up test). Chinese Version of International Spinal Cord Injury Quality of Life Basic Data Set Version 1.0 (SCIQ,Brain wave activity before (pre-test), immediately after the test (post-test), and 4-week follow-up (follow-up test). resting electroencephalography (EEG) with eyes closed