IRCT20240515061806N1RecruitingPhase 2
Comparison of adjuvant tadalafil and tamsulosin with tamsulosin alone in patients undergoing extracorporeal shockwave lithotripsy of renal stones
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Recruiting
- Enrollment
- 160
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to no limit (—)
- Sex
- All
Inclusion Criteria
- •Patients older than 18 years
- •Having stones with a size between 5 and 20 mm in the kidney and proximal ureter
Exclusion Criteria
- •Having coagulation disorders
- •Creatinine clearance below 50 ml/min
- •Liver dysfunction
- •Urgent surgery is needed to remove stone blockage
- •Presence of positive urine culture
- •Patients with simultaneous unilateral or bilateral ureteral stones
- •The distance between the stone and the skin is more than 12 cm
- •History of previous unsuccessful extracorporeal lithotripsy
- •Use of nitroglycerin and netirocanthine
- •Lack of consent to participate in the study
- •Systolic blood pressure below 90 mm Hg at the time of treatment initiation
- •History of cataract
- •History of hypersensitivity after taking tamsulosin or tadalafil
- •History of back ache
- •History of Severe digestive disorders after treatment
- •History of priapism
Investigators
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