The incidence of late-onset Pompe disease in subjects with obstructive sleep apnea

Completed

• Conditions: rare muscle disorder; sleep disorder; 10046304

• Registration Number: NL-OMON36188
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 500

Inclusion Criteria

a.age over 18 years
b.a diagnosis of OSAS no older than 5 years
c. Diagnosis of OSAS confirmed by polysomnography with a apneu-hypopneu index higher than 15

Exclusion Criteria

a.severe left-sided heart failure
b.active psychiater-diagnosed mental disorder, thereby not able to provide informed consent
c.clinical suspicion on vascular cerebral accident located in the ventral medulla of the brain stem.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>deficiency of the lysosomal enzyme acid -glucosidase </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>none</p><br>