Prevalence, Mechanisms, and Outcome of Tricuspid Valve Regurgitation in the Elderly
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 700
- 试验地点
- 1
- 主要终点
- Prevalence of tricuspid valve regurgitation in the elderly
研究概览
简要总结
Tricuspid regurgitation (TR) is the second most common VHD after MR. Its prevalence also increases with age, with an estimated incidence of up to 6% in elderly population. When adjusted to age (among other confounders), survival is worse for patients with moderate and severe TR. We aim to explore the prevalence, mechanisms, and clinical implications of tricuspid valve regurgitation in elderly subjects screened at a tertiary center in Cairo, Egypt.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All comer patients ≥60-year-old presenting to the echocardiography clinic
排除标准
- •Poor acoustic window.
结局指标
主要结局
Prevalence of tricuspid valve regurgitation in the elderly
时间窗: Baseline (at enrolment)
Prevalence of mild, moderate, and severe TR in enrolled patients
All-cause mortality
时间窗: At 6 months
Incidence of death from any cause
Rehospitalization for congestive heart failure
时间窗: At 6 months
Incidence of new-onset or worsening signs and symptoms of heart failure that required urgent therapy and resulted in hospitalization.
Cardiovascular mortality
时间窗: At 6 months
Incidence of cardiovascular death, defined as death attributable to myocardial ischemia and infarction, heart failure, cardiac arrest because of other or unknown cause, or cerebrovascular accident.
次要结局
- Classification of tricuspid valve regurgitation in the elderly(Baseline)
- Change in New York Heart Association (NYHA) functional class(At 6, 12 and 60 months)
- All-cause mortality(At 12 and 60 months)
- Cardiovascular mortality(At 12 and 60 months)
- Rehospitalization for congestive heart failure(At 12 and 60 months)
研究者
Mohammad Abdelghani
Lecturer of Cardiology - Cardiology Consultant
Al-Azhar University