Effects of Vitamin D Supplementation on Antimycobacterial Immunity

Not Applicable

Completed

• Conditions: Tuberculosis

• Registration Number: NCT00157066
• Lead Sponsor: Barts & The London NHS Trust

Brief Summary

The purpose of this study is to determine how vitamin D supplementation (ergocalciferol) affects the immune response to mycobacterial infection.

Detailed Description

Not available

Study Timeline

• Study Start: 2002-12
• Study First Submitted: 2005-09-08
• Study First Submitted QC: 2005-09-08
• Study First Posted: 2005-09-12
• Study Completion: 2006-09
• Status Verified: 2007-01
• Last Update Submitted: 2007-01-05
• Last Update Posted: 2007-01-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 230

Inclusion Criteria

• Adult
• Tuberculosis (TB) contact or TB patient

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Exclusion Criteria

• Pregnancy
• Breastfeeding
• Hyperparathyroidism
• Sarcoidosis
• Renal failure
• HIV infection

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Bacillus Calmette-Guerin (BCG) lux whole blood assay

Secondary Outcome Measures

Name	Time	Method
Antigen-stimulated whole blood interferon gamma production

Trial Locations

Locations (1)

Tuberculosis Clinic, Newham Chest Clinic; 🇬🇧 London, United Kingdom