COPD and Air Travel: Oxygen Equipment and Pre-flight Titration of Supplemental Oxygen
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- PaO2 obtained from oxygen titration during HAST vs hypobaric chamber
研究概览
简要总结
The purpose of this study is to evaluate if supplemental oxygen during air travel can be reliably titrated using a Hypoxia-altitude simulation test (HAST). Also, the effect of oxygen supplementation given with the various oxygen equipment allowed for air travel is studied.
详细描述
International guidelines recommend supplemental oxygen if PaO2 < 6.7 kPa (50 mmHg) during air travel. Hypobaric chamber exposure is the ideal test but is not widely available. In clinical practice, the HAST has been recommended as the preferable test for pre-flight evaluation, and is used with increasing frequency. The oxygen dose during air travel has been recommended titrated during HAST. In the study, supplemental oxygen titration during hypobaric chamber exposure is compared to oxygen titration during HAST, to evaluate if HAST can be used with confidence to titrate the amount of supplemental oxygen needed during air travel.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •COPD patients who have performed a Hypoxia-altitude simulation test with a PaO2 < 6.7 kPa
排除标准
- •exacerbation or pneumothorax within the previous six weeks
- •pulmonary disease other than COPD
- •cerebrovascular or symptomatic cardiovascular disease
- •claustrophobia
- •inability to equalize pressure in the middle ear
结局指标
主要结局
PaO2 obtained from oxygen titration during HAST vs hypobaric chamber
时间窗: 1 day
次要结局
未报告次要终点