NL-OMON49020RecruitingPhase 2
Imaging tumor angiogenesis using [18F]-DCFPyL PET/CT in patients with colon, gastric and pancreatic cancer. - PSMA PET colon, gastric and pancreatic cancer.
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Recruiting
- Enrollment
- 30
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •Patients aged 18 years or older.
- •Diagnosis of primary T3-4N0-2M0-1 colorectal adenocarcinoma (cohort 1) or
- •primary gastric carcinoma (cohort 2), or primary pancreatic cancer (cohort 3).
- •Absence of any psychological, familial, sociological or geographical condition
- •potentially hampering compliance with the study protocol and follow-up
- •schedule; those conditions should be discussed with the patient before
- •registration in the trial.
- •Before patient registration, written informed consent must be given according
- •to ICH/GCP, and national/local regulations.
Exclusion Criteria
- •Any condition that in the opinion of the investigator could potentially
- •jeopardize the health status of the patient.
- •Medical or psychiatric conditions that compromise the patient*s ability to give
- •informed consent. Presence of any psychological, familial, sociological or
- •geographical condition potentially hampering compliance with the study protocol
- •and follow-up schedule.
- •Prior radiotherapy to the abdomen (cohort 1 and 2) and/or thorax (cohort 2).
- •Unacceptable known (clinically significant) cardiovascular or pulmonary
- •disease, renal or liver dysfunction.
- •Known hypersensitivity to drugs comparative to PSMA-DCFPyL, or any of their
- •excipients or to any component of [18F]-DCFPyL.
- •Inability to undergo PET/CT scanning (e.g. claustrophobia, weight limits or
- •inability to tolerate lying for the duration of a PET/CT scan (~30 min).
Investigators
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