EUCTR2012-003011-58-HU进行中（未招募）1 期
A randomized, double-blind, placebo-controlled, event-driven trial of quarterly subcutaneous canakinumab in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with elevated hsCRP: OGTT (Oral Glucose Tolerance Test) study to examine the long term effects (3-4 years) of canakinumab in T2DM on endogenous insulin secretion and insulin resistance. - CANTOS sub-study 2
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1. Written informed consent form
- •2. Meet main study eligibility criteria listed in Section 4.1 and 4.2 of protocol CACZ885M2301 and agreed to participate in CANTOS main study
- •3. T2D at baseline per CACZ885M2301 protocol criteria and be on a stable anti-hyperglycemic medication for at least 4 weeks prior to the baseline OGTT test
- •4. Willing to have the OGTT assessment started before 10 am
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 180
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 120
排除标准
- •Pregnant or nursing (lactation) women
- •Women of child-bearing potential
- •Any of the following concomitent diseases:
- •1. Planned coronary revascularization
- •2. major non cardiac surgical or endoscopic procedure within past 6 months
- •Uncontrolled hypertension
研究者
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