Citizen Action for Sustainable Dengue Control in Sub-Saharan Africa
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Aedes aegypti mean number per trap per day
研究概览
简要总结
This project focuses on addressing arboviral outbreaks in Ivory Coast by involving local communities in the sustainable control of Aedes mosquitoes, utilizing scientific advice and environmental interventions. It will evaluate the impact of a participatory strategy on decreasing mosquito populations and the risk of virus transmission, aiming to provide insights for policy development on disease prevention.
详细描述
This project targets the growing threat of Aedes mosquito-borne diseases such as dengue in Africa, focusing on the Anono and Gbagba communities in Abidjan, Ivory Coast, by transitioning from traditional control approaches to a community-driven strategy. It focuses on educating and involving communities in the design of sustainable mosquito management measures, such as breeding site eradication and adult mosquito capturing, with scientific experts guiding the efforts. The approach will entail conducting sociocultural surveys and interactive workshops while also encouraging local participation and multi-sectoral collaboration. A randomized controlled trial (RCT) will test this effectiveness of this novel integrated community-based participatory intervention approach in reducing the transmission of Aedes mosquito and other arboviruses. This effort seeks to develop a scalable model for arboviral disease control, promote community resilience, and inform policy recommendations for better public health outcomes in resource-constrained urban settings.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
盲法说明
Statistician unaware of the arms allocation
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Geographical location: households must be located within the designated clusters in the two districts involved in the trial.
- •Participation in cluster arms: households must belong to a cluster that is assigned to one of the four arms (
- •Community-based larval source management, 3 Enhanced Aedes adults trapping (BG-GAT),
- •Enhanced Aedes adults trapping (BG-GAT) + Community-based larval source management).
- •Willingness to participate: households agreed to allow researchers to place mosquito traps and conduct larval and adult mosquito surveys.
- •Socio-Environmental Data: households must agree and provide consent to participate to the socio-environmental questionnaire.
排除标准
- •Outside of trial clusters: households located outside the designated clusters in the two districts were excluded.
- •Refusal to participate: households that do not consent to mosquito trap placement or surveys
- •Inaccessibility: households that are not accessible for regular visits or data collection (e.g., due to relocation or difficult terrain).
研究组 & 干预措施
Control
Non-intervened control arm: no community-based larval source management (LSM) or BG-GAT intervention
Community-based larval source management
LSM intervention arm: Aedes larval source reduction carried out by trained and supervised local community members
干预措施: Community-based larval source management (Behavioral)
Enhanced Aedes adults trapping (BG-GAT)
BG-GAT intervention arm: Aedes adult mass trapping by BG-GAT set up and maintained by trained and supervised local community members
干预措施: Enhanced Aedes adults trapping (BG-GAT) (Device)
Community-based larval source management + Enhanced Aedes adults trapping (BG-GAT)
Combined LSM and BG-GAT intervention arm: simultaneous Aedes larval source reduction and Aedes adult mass trapping by BG-GAT carried out by trained and supervised local community members
干预措施: Community-based larval source management with Enhanced Aedes adults trapping (BG-GAT) (Combination Product)
结局指标
主要结局
Aedes aegypti mean number per trap per day
时间窗: Continuously during months 1-4 (baseline) and months 5-17 (trial)
Biting rate is the mean number of Aedes females per trap and per day. The proportion of unfed, fed, half-gravid and gravid females will be estimated.
次要结局
- House index(Before (month 1), twice during (month 4, 8) and once at the end of the trial (month 12))
- Pupal indices: pupae per person index, pupa index and pupae per hectare index(Before (month 1), twice during (month 4, 8) and once at the end of the trial (month 12))
- Adults: parity rate(Continuously during months 1-4 (baseline) and months 5-17 (trial))
- Knowledge, attitudes, and practices on Dengue prevention among the population of Cocody-Bingerville(Before (month 1) the start of the trial and at the end of the trial (month 12))
- Mapping and describe Aedes aegypti breeding sites, focusing on their geographic and ecological characteristics. This mapping will be used to enhance targeted larval control efforts in these areas.(Before (month 1) the start of the trial and at the end of the trial (month 12))
- Container index(before (month 1), twice during (month 4, 8) and once at the end of the trial (month 12))
- Breteau index(Before (month 1), twice during (month 4, 8) and once at the end of the trial (month 12))