Exploring Triggers for Delayed Quadriceps Strength Recovery in TKA Patients

Not Applicable

Recruiting

Conditions: Osteoarthritis of the knee, Rheumatoid arthritis
OA, RA

Registration Number: JPRN-jRCT1032230548

Lead Sponsor: Kikuchi Naoya

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 80

Inclusion Criteria

1. Patients 40 years of age or older capable of giving written consent.
2. Patients who have been diagnosed by a physician as having knee joint disease (e.g., knee OA or RA) on x-ray and MRI images, and who are scheduled to undergo TKA.
3. Patients must be observable for the entire study period.

Exclusion Criteria

1. Patients who are not considered appropriate for the study by the investigator.
2. Patients with bleeding tendency that may cause problems in training, severe complications (respiratory or circulatory diseases) that may interfere with daily life, infectious diseases, etc.
3. Patients with a history of other artificial joint surgery on the same side as the limb in which the TKA was performed.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Evaluation of skeletal muscles and non-contractile tissues around the knee joint (muscle cross-sectional area, muscle thickness, and muscle brightness) using an ultrasound imaging system. Target muscles to be imaged: MAIN rectus femoris, SUB medial vastus medialis, vastus lateralis, and vastus medialis.<br>2. Evaluation of knee isokinetic/isotonic knee extension and flexion muscle strength (using BIODEX system4).

Secondary Outcome Measures

Name	Time	Method
1. Body Composition Testing; Body Composition Analyzer In Body720 (BioSpace Corporation).<br>2. Knee joint flexion/extension range of motion evaluation.<br>3. Grip strength and leg circumference measurement.<br>4. Physical function assessment; 6m walking speed or 5 times chair stand test, Time Up & Go test (10m walking speed or 30 times chair stand test will be conducted if possible).<br>5. Subjective and patient-oriented assessment of the knee joint; KOOS (Knee Injury and Osteoarthritis Outcome Score), KSS (Knee Society Scores).