Prognosis of Guillain-Barré Syndrome in Children.
Completed
- Conditions
- acute inflammatory demyelinating polyneuropathy (AIDP)no lay-term10034606
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
· Fulfilling the diagnostic criteria for GBS [Asbury 1990]
· Age of diagnosis of GBS 18 years or less
· Diagnosis of GBS was made in 1987 or thereafter
· Patients were either treated at the ward or outpatient clinic of the department of Paediatric Neurology of the Sophia Children*s Hospital, Erasmus MC, or were included in the earlier clinical trials of the GBS study group of the Erasmus MC
· Written informed consent given by the patient and/or parents/care takers
Exclusion Criteria
· Additional diseases or disorders at the time of diagnosis that may influence the endpoints
· Diagnosis of GBS less than 6 month ago
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Main study parameter/endpoint<br /><br>Residual effects on long-term outcome, with respect to nerve physiology<br /><br>dysfunction, neurological impairment, restrictions in daily activity and<br /><br>participation, and quality of life. Long-term outcome will be defined at least<br /><br>six months from diagnosis, the period in which most recovery occurs. The<br /><br>outcome levels will be determined by using various questionnaires and physical<br /><br>tests that are validated for the appropriate age categories. By using these<br /><br>tests, preferably the results obtained in patients from various ages can be<br /><br>combined. </p><br>
- Secondary Outcome Measures
Name Time Method