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Factors Associated with Coronary Artery Calcification and Cardiovascular Outcome Among Pre-Dialysis Chronic Kidney Disease Patients in Phramongkutklao hospital

Completed
Conditions
Factors associated with coronary calcium score and incidence of composited cardiovascular events which defined as death, MI or heart failure within 6 months after enrollment in CKD patients who have intermediate risk for coronary heart disease. Patients who had received dialysis or coronary revascularization were excluded.
CKD, coronary calcium score, Osteocalcin
Registration Number
TCTR20220519006
Lead Sponsor
Department of Internal Medicine, Phramongkutklao Hospital
Brief Summary

The CAC score showed inversely correlation with GFR level. Increasing Osteocalcin level and T2Dm with TOD were significantly correlated with increasing CAC score in pre-dialysis CKD patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
88
Inclusion Criteria

1. Age over 18 years old
2. Patients with chronic kidney disease who have not received hemodialysis and stable GFR more than 3 month
3. Patients who have previously checked the coronary artery calcification from CT Coronary artery calcification score within 1 year from the date of study or a new patient with an indication of the existing coronary artery calcification from the existing.

Exclusion Criteria

Patients who had received dialysis or coronary revascularization were excluded

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
factors associated with coronary calcium score at 6 month after enrollment Agaston coronary calcium score
Secondary Outcome Measures
NameTimeMethod
Composited cardiovascular events which defined as death, MI or heart failure at 6 months after enrollment Incident of composited cardiovascular event
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