A comparative study of epidural nalbuphine versus fentanyl for analgesic efficacy in patients undergoing infraumbilical surgeries under spinal anesthesia.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Analgesic efficacy of epidural nalbuphine versus fentanyl in terms of duration of Analgesia in patients undergoing infraumbilical surgeries under spinal anesthesia in 24 hours
研究概览
简要总结
This study is a randomized control, double blinded study, comparing the analgesic efficacy of epidural nalbuphine 5mg versus fentanyl 50 mcg in patients undergoing infraumbilical surgeries under spinal anesthesia that will be conducted in bangalore medical college and research institute and the allied hospitals. The primary outcome is to compare the analgesic efficacy and secondary outcome is to assess the onset of sensory and motor blockade, duration of motor blockade, 2 segment regression, VAS scores, ramsay sedation scores and time for first rescue analgesic.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients giving consent, ASA grade 1 and 2, BMI 18 to 29 kg/m^2.
排除标准
- •Allergy to local anesthetic, spine deformity, coagulopathy,chronic pain syndromes, cardiac diseases, liver and kidney dysfunction, neurological disorders, pregnancy and breastfeeding mothers, technical failure, patients on tricyclic antidepressants, alpha 2 agonist and opioids.
结局指标
主要结局
Analgesic efficacy of epidural nalbuphine versus fentanyl in terms of duration of Analgesia in patients undergoing infraumbilical surgeries under spinal anesthesia in 24 hours
时间窗: Analgesic efficacy of epidural nalbuphine versus fentanyl in terms of duration of Analgesia in patients undergoing infraumbilical surgeries under spinal anesthesia in 24 hours
次要结局
- Compare onset of sensory & motor blockade, duration of motor blockade, 2 segment regression, VAS, ramsay sedation scale, time of first rescue analgesia.(In 24 hrs)
- Assess hemodynamic parameters perioperatively(24 hours)
- Assess incidence of any side effects of study drugs(In 24 hours)
研究者
Dr Varshini G
Bangalore medical college and research institute