Translating the ABCS Into HIV Care

Not Applicable

Active, not recruiting

• Conditions: HIV; Cardiovascular Risk Factor
• Interventions: Behavioral: ABCS training

• Registration Number: NCT03902431
• Lead Sponsor: University of Rochester

Brief Summary

The overall objective of this project is to develop and rigorously test implementation strategies to address the gap in scientific knowledge of lower use of evidence-based interventions commonly referred to as the ABCS (aspirin, blood pressure control, cholesterol control, and smoking cessation)which contributes to the growing CVD morbidity and mortality among PLH.

Detailed Description

Our project has two major aims:

Aim 1: To assess the impact of the implementation of an evidence-based, multilevel strategy to reduce cardiovascular vascular disease (CVD) among PLH.

Aim 2: To assess the process of implementation of these strategies using RE-AIM QuEST. Using both quantitative and qualitative methods, we evaluate the process of implementation by assessing Reach, \[Effectiveness addressed in Aim 1\], Adoption, Implementation and Maintenance whilst integrating Qualitative Evaluation for Systematic Translation.

Study Timeline

• Study First Submitted: 2019-04-01
• Study First Submitted QC: 2019-04-01
• Study First Posted: 2019-04-04
• Study Start: 2019-09-26
• Primary Completion: 2022-08-31
• Status Verified: 2023-07
• Last Update Submitted: 2023-09-20
• Last Update Posted: 2023-09-22
• Study Completion: 2024-05-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 4277

Inclusion Criteria

Sites:

• Serve a cohort of at least 100 HIV patients
• Have an Electronic Health Record (EHR)
• Agree to collaborate on implementing feasible adaptations of intervention strategies

Patients:

• Patient of the site with a diagnosis of HIV
• Age 40-79 years
• ≥5% risk for CVD as calculated using the ASCVD Risk Estimator Plus
• Willing to participate
• No plans to leave the site in the next 12 months
• Proficient in either English or Spanish
• Own a cell phone with texting capabilities

Clinicians:

• Physicians, Physicians Assistants, or Nurse Practitioners who provide direct HIV care to patients
• Work at a participating site
• Willing to implement the project's intervention strategies

Exclusion Criteria

Patients:

• Currently participating in another CVD trial
• Have experienced a prior cardiac or vascular event such as myocardial infarction (MI) or cerebrovascular accident (CVA)
• Have had a CVD procedure such as installation of a stent or angioplasty
• Have peripheral vascular disease, intermittent claudication or peripheral arterial disease
• Are pregnant
• Lacks capacity to consent

Clinicians:

• Planning to leave the site within the next 12 months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Training	ABCS training	CVD risk after the patient and clinician training

Primary Outcome Measures

Name	Time	Method
10-year CVD risk reduction	12 months	This will be based on the ACVSD risk calculator

Trial Locations

Locations (1)

University of Rochester; 🇺🇸 Rochester, New York, United States