Early and Intermediate Term Outcomes of Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- regurgitation
研究概览
简要总结
Thoraco-laparoscopic partial esophagogastrectomy has emerged as a promising minimally invasive alternative, combining thoracoscopy and laparoscopy to reduce the trauma associated with open surgery.Early and intermediate-term outcomes provide critical information on both the oncological efficacy and functional benefits of the procedure. By examining recurrence rates within the first 12-24 months, this study will provide valuable insights into the oncological robustness of this approach compared to more invasive approaches.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients diagnosed with resectable esophageal cancer (stages I-III).
- •Suitable for thoraco-laparoscopic partial esophagogastrectomy.
- •Eastern Cooperative Oncology Group (ECOG) performance status 0-2.
排除标准
- •Presence of distant metastasis at diagnosis.
- •History of previous esophageal or gastric surgery.
- •Contraindications to laparoscopy or thoracoscopy.
研究组 & 干预措施
Thoraco-laparoscopic partial esophagogastrectomy
Patients diagnosed with resectable esophageal cancer will undergo thoraco-laparoscopic partial esophagogastrectomy
干预措施: Thoraco-laparoscopic partial esophagogastrectomy (Procedure)
结局指标
主要结局
regurgitation
时间窗: Collected at one month, and 12 months post-surgery.
yes or no
Immediate Postoperative complications
时间窗: first month post operative
30-day morbidity and mortality (using Clavien-Dindo classification)
Dysphagia
时间窗: Collected at base line preoperative,one month, and 12 months post-surgery.
yes or no
resection margin status
时间窗: 2 weeks postoperative
resection margin status (R0/R1/R2)
lymph node yield.
时间窗: first month post operative
number of lymph nodes in specimen
次要结局
- recurrence rate(first year post operative)
- body mass index(Collected at base line preoperative,one month, and 12 months post-surgery.)
- serum albumin(Collected at base line preoperative,one month, and 12 months post-surgery.)
研究者
Ahmed Mahrous Salaheldin
assisstant lecturer of general surgery
Sohag University