Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer

Not Applicable

Not yet recruiting

• Conditions: Esophageal Cancer

• Registration Number: NCT06879483
• Lead Sponsor: Sohag University

Brief Summary

Thoraco-laparoscopic partial esophagogastrectomy has emerged as a promising minimally invasive alternative, combining thoracoscopy and laparoscopy to reduce the trauma associated with open surgery.Early and intermediate-term outcomes provide critical information on both the oncological efficacy and functional benefits of the procedure. By examining recurrence rates within the first 12-24 months, this study will provide valuable insights into the oncological robustness of this approach compared to more invasive approaches.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-02
• Study First Submitted: 2025-03-06
• Study First Submitted QC: 2025-03-13
• Last Update Submitted: 2025-03-13
• Study First Posted: 2025-03-17
• Last Update Posted: 2025-03-17
• Study Start: 2025-09-01
• Primary Completion: 2026-09-01
• Study Completion: 2027-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients diagnosed with resectable esophageal cancer (stages I-III).
• Suitable for thoraco-laparoscopic partial esophagogastrectomy.
• Eastern Cooperative Oncology Group (ECOG) performance status 0-2.

Exclusion Criteria

• Presence of distant metastasis at diagnosis.
• History of previous esophageal or gastric surgery.
• Contraindications to laparoscopy or thoracoscopy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Immediate Postoperative complications	first month post operative	30-day morbidity and mortality (using Clavien-Dindo classification)
Dysphagia	Collected at base line preoperative,one month, and 12 months post-surgery.	yes or no
resection margin status	2 weeks postoperative	resection margin status (R0/R1/R2)
lymph node yield.	first month post operative	number of lymph nodes in specimen
regurgitation	Collected at one month, and 12 months post-surgery.	yes or no

Secondary Outcome Measures

Name	Time	Method
recurrence rate	first year post operative
body mass index	Collected at base line preoperative,one month, and 12 months post-surgery.
serum albumin	Collected at base line preoperative,one month, and 12 months post-surgery.

Trial Locations

Locations (1)

Sohag Faculty of Medicine; 🇪🇬 Sohag, Egypt