Comparative evaluation of salivary macrophage inflammatory protein -1α (MIP-1α) levels in periodontitis subjects post photo-biomodulation combined with non-surgical periodontal therapy and non-surgical periodontal therapy alone: A prospective interventional study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Improvement in periodontal health and biochemical parameters
研究概览
简要总结
participants with stage 2 and grade B periodontitis are identified and will be enrolled in the study, the participants distributed in 2 groups, one group with 30 participants will receive non-surgical periodontal therapy alone and the 2nd group will receive Non-surgical periodontal therapy with photobiomodulation with diode laser. all clinical parameters along with Salivary MIP-1 alpha levels will be assessed at the base line and post 21 days of intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •systemically healthy patients with stage 2 and grade B of generalized periodontitis, between age of 30 to 60 years.
排除标准
- •pregnant, lactating females, on antibiotic therapy or who has a previous history of peridontitis.
结局指标
主要结局
Improvement in periodontal health and biochemical parameters
时间窗: the clinical parameters and biochemical parameters, will be assessed at baseline and post 21 days in both the groups using abbkine CCL3 | kit with ELISA reader for bio-chemical analysis, and using plaque index, gingival index, calculus index, Pocket probing depth and clinical attachment loss, at both baseline and post 21 days
次要结局
- Reduction in Pocket probing depth, Clinical attachment loss, Gingival index, Plaque index(post 21 days of intervention)
研究者
Fazal Mujawar
School of dental sciences, KVV, karad